TESE (testicular sperm extraction) is a technique of sperm retrieval directly from a testicle and is used in assisted reproduction procedures in certain cases of sperm-free semen.
Indications for TESE are diagnoses of: azoospermia, primary testicular failure, congenital bilateral absence of the vas deferens, complete necrozoospermia or unsuccessful bilateral reconstruction of vas deferens following vasectomy. Clinical justification of the biopsy is assessed by the doctor based on the test findings and a patient’s medical history. The testicular biopsy is performed under analgosedation (short-lasting anaesthesia). During the procedure, testicular tissue samples are collected to look for sperm cells. In 75% of analyses, the tissue contains sperm cells and/or spermatogenic cells. The cells collected via biopsy can be directly used for in vitro fertilisation (ICSI) or can be frozen.